Human Plasma High Density Lipoprotein

Determination of high density lipoprotein-cholesterol in stored human plasma.

This study was performed to determine the effect of frozen and unfrozen storage on plasma high density lipoprotein (HDL) cholesterol analysis. HDL-cholesterol was determined, following removal of the other lipoproteins by precipitation with heparin and MnCl(2), in fresh plasma samples and in aliquots of the samples that had been stored 1) unfrozen (4 degrees C), up to 14 days, 2) frozen (-20 de...

Apoprotein exchange between human high-density-lipoprotein subfractions (high-density-lipoprotein subfractions 2 and 3) [proceedings].

centrifugation restored these increases when included in the heparin-containing medium at concentrations of 10-8Opg of protein/ml. The ability of heparin to stimulate the release of lipoprotein lipase from human adipose tissue in vitro has been demonstrated by several groups of workers (Elkeles, 1974). That this release can be closely correlated with triacylglycerol clearance provided further e...

High density Lipoprotein; What to Measure: Quality or Quantity?

High -density lipoprotein cholesterol as a predictor for diabetes mellitus

Background: Diabetes is a prevalent chronic disease around the world. To evaluate risk of diabetes comprehensively, we developed a score model for the risk prediction with HDL-C as a protective factor. Methods: We extracted physical examination data of 2728 individuals. The data contain 18 demographic and clinical variables. To identify the statistical significant feature variables, the backwa...

Computational Lipidology: Predicting Lipoprotein Density Profiles in Human Blood Plasma

Monitoring cholesterol levels is strongly recommended to identify patients at risk for myocardial infarction. However, clinical markers beyond "bad" and "good" cholesterol are needed to precisely predict individual lipid disorders. Our work contributes to this aim by bringing together experiment and theory. We developed a novel computer-based model of the human plasma lipoprotein metabolism in ...